What was advertised in a colonial American newspaper 250 years ago this week?

“They manufacture and sell as usual at Frederick-Town.”
According to their advertisement in the Pennsylvania Gazette, Hamilton and Leiper sold tobacco and snuff at several locations. For consumers in Philadelphia, they listed their location as “Second-street, between Market and Arch-streets.” The primary purpose of their advertisement in the May 2, 1771, edition of the Pennsylvania Gazette, however, was to inform customers in Maryland that they had “established a MANUFACTORY in Market-street, Baltimore.” At that location, they sold “the various kinds of manufactured TOBACCO and SNUFF (of the best quality) on the most reasonable terms.” In addition, the tobacconists declared that they “manufacture and sell as usual at Frederick-Town” in western Maryland. Altogether, Hamilton and Leiper sold tobacco and snuff in three towns in two colonies, their multiple locations providing for “the conveniency of their customers.”
Their advertisement in the Pennsylvania Gazette also testified to the reach of that newspaper in the early 1770s. Baltimore would not have its own newspaper until August 1773. Fredericktown (now Frederick) did not have a newspaper until after the American Revolution. For half a century, the Pennsylvania Gazette served as a regional newspaper for readers in Pennsylvania, Delaware, Maryland, and New Jersey. Although most of the advertisers who promoted consumers goods and services in its pages were located in Philadelphia, the Pennsylvania Gazette also carried notices from Lancaster, Pennsylvania; Wilmington, Delaware; Baltimore and Frederick, Maryland; Burlington and Trenton, New Jersey; and several other towns in those colonies. Similarly, the Pennsylvania Gazette carried legal notices and advertisements about runaway apprentices and indentured servants and enslaved people who liberated themselves submitted by colonists throughout the region. In the same column as Hamilton and Leiper’s advertisement, Henry Wells, a jailer, described a runaway servant who made his escape from William Anders or Andrews in Joppa, Maryland, but had been taken into custody and confined in Dover, Delaware.
Several colonies constituted a single media market for the Pennsylvania Gazette and other newspapers published in Philadelphia before the revolution. Enterprising entrepreneurs like Hamilton and Leiper also recognized the potential to create larger markets for their wares rather than serve only a single town and its hinterlands. In the early 1770s, they branched out from locations in Philadelphia and Frederick to a third location in Baltimore. Advertisements in the Pennsylvania Gazette alerted consumers in and near all three places about the tobacco and snuff that Hamilton and Leiper sold at their several convenient locations.